Forfar will be missing Iain Campbell and Michael Dunlop as they host East Fife at Station Park, with manager Dick Campbell also unable to call on four other Loons.
Darren Dods is still struggling with a hamstring problem, Marvin Andrews has an ankle injury, Keith Gibson remains out following knee surgery and Gary Fusco has work commitments.
Former Scotland goalkeeper Rab Douglas will be on the bench after joining this week in a playing and coaching capacity, with Campbell saying: "We brought in 11 new players but we are actually short of numbers for this game.
"I will bring in a couple of boys from the youth squad to be on the bench."
New look East Fife will be without summer recruit Adam Bouzid as he starts a two-match ban following his dismissal in a friendly against Cowdenbeath.
Recently-appointed manager Willie Aitchison is looking forward to being in charge for his first competitive game.
He said: "Apart for a poor 10-minute spell against Hamilton Accies last Saturday, when we lost three goals, our pre-season went well.
"We have brought in a lot of new faces but we ran Alloa, Wolves and Kilmarnock close so I am really keen for that first whistle.
"However we are up against an experienced manager and experienced players so it will not be easy."