Leeds boss Brian McDermott will once again be without Dexter Blackstock for the clash with Wigan.
The on-loan Nottingham Forest forward missed Saturday's 1-0 defeat to Blackburn with a swollen knee and is to undergo scans to determine the extent of his injury.
McDermott will run the rule over striker Ross McCormack, who sustained a hip injury against Rovers, and defender Tom Lees (knee).
Defender Scott Wootton remains sidelined with an ankle problem but Sam Byram could return to the starting XI after recovering from a thigh injury.
Scott Carson could replace Lee Nicholls in goal as Wigan look to avoid a fourth successive defeat.
Fit-again Carson (ankle) watched on from the bench on Sunday as Latics lost 3-1 at home to Derby and is set to make his first appearance since October 24. Fellow keeper Ali Al Habsi (knee) has returned to training but this game will come too soon.
Gary Caldwell and Shaun Maloney (both hip) remain on the sidelines but Ivan Ramis is set to start again after featuring for the first time since January at the weekend.
Caretaker management team Graham Barrow and Sandy Stewart will be in charge for the trip to Elland Road and they could freshen things up in a bid to stop the rot, with Grant Holt and Ryan Shotton among those in contention for recalls.