Brentford will check on midfield duo Jonathan Douglas and Adam Forshaw for the visit of Crewe.
Douglas had to go off at half-time against Staines Town last weekend after sustaining a foot injury while Forshaw missed the 5-0 FA Cup victory due to an ankle knock.
Striker Will Grigg will be unavailable as he is on international duty in Turkey with the Northern Ireland squad so Clayton Donaldson leads the line against his old club.
Defender Harlee Dean is back having missed out last weekend through suspension after collecting five yellow cards this season.
Crewe manager Steve Davis is set to be without both Ryan Colclough and Matt Tootle for the trip.
Midfielder Colclough, who has been out for over a month with hip and groin problems, has been forced to sit out training this week with a tight hamstring, while full-back Tootle is still struggling with a foot injury.
Ollie Turton and Mathias Pogba remain on the sidelines with knee injuries but George Ray could return after missing last weekend's FA Cup tie against Wycombe with a tight hamstring.
The Alex are chasing their first win in five games in all competitions and only a second on the road in League One.