Annan will look to build on last Saturday's historic win over Rangers by seeing off Clyde at Galabank but goalkeeper Craig Summersgill remains out with a back injury.
Striker Graeme Ramage is also missing due to a knee knock however Peter Watson could return after a reserve outing following a thigh strain.
Black and Gold boss Jim Chapman said: ``This will be a test for the players as we showed last week what we are capable of when we raise our game. We know have to play to that standard in front of a much smaller crowd.
``Last weekend our concentration levels were fantastic and we hardly put a foot wrong. Now we need to show that in the type of game where we were making mistakes in before.''
Clyde will look to win at Annan's Galabank ground for a second time this season, however the Bully Wee's plans have been hit by injuries to defensive trio of Michael Oliver, Gavin Brown and David Marsh.
Oliver has an ankle problem, Brown is struggling with a hamstring strain and Marsh has torn an abductor muscle with Clyde looking to make up for last weekend's 3-2 defeat from Queen's Park.
Manager Jim Duffy said: ``We played well last week and should have won. We had a poor 10 minutes and that cost us but if we can cut lapses in concentration out then we can do well at Annan.
``It will not be easy as their result at Ibrox was sensational and their confidence will be sky high as a result.''