Jimmy Kebe will miss Reading's Barclays Premier League encounter with Liverpool at the Madejski Stadium because of a groin problem.
Fellow midfielder Hope Akpan is a major doubt for the match because of an ankle injury sustained in last Saturday 2-0 defeat to Southampton.
Royals boss Nigel Adkins said Reading have further niggles, but no other players are expected to be ruled out.
Liverpool manager Brendan Rodgers was sacked by Reading in 2009 after just six months in charge, but Adkins doubts there will be any special desire to demonstrate to his former employers that they made a mistake.
``Brendan doesn't have anything to prove to us. He's a fantastic manager,'' he said.
``He was here, was very successful at Swansea and is doing a fantastic job at Liverpool. He's a footballing man who improves his players.
``He has teams that are really exciting to watch, so I don't believe he has anything to prove to anybody.''
Adkins hinted that his players have the six matches left in Reading's season to prove they should remain in his plans for next season.
``Every player knows that the transfer window opens at the end of the season and that all clubs do business, moving people around. Here will be no exception,'' he said.
``The players have been spot on in training and the attitude of the players tells me they want to stay at Reading.''
Forward Raheem Sterling will be absent again for Liverpool as the club continue to manage the teenager's thigh injury.
Winger Stewart Downing, who played in last weekend's goalless draw with West Ham despite illness, is now fully recovered.
Forward Fabio Borini and midfielder Joe Allen (both shoulder) are sidelined, as is defender Martin Kelly (knee).
Star striker Luis Suarez has not scored for three games but, after drawing another blank against West Ham last weekend, boss Brendan Rodgers insists his star man is not feeling the effects of a long campaign, during which at times he has carried the side single-handedly.
``What he maybe showed last weekend was he is human, but the level of his consistency this season has been incredible,'' said the Northern Irishman.
``He showed sometimes he is not always going to be nine or 10 out of 10. Luis may have not have been a nine out of 10 but he was certainly a seven for his work-rate and his intensity.
``From time to time he will have games like that but it just shows you the level he has reached this year, where he can still have a good game but because he doesn't score he is regarded as not being at as high a level.
``He has that mindset where he wants to play every game and we're certainly better off with him in the team than out of it.''