Millwall boss Kenny Jackett is expected to shuffle his pack ahead of his side's meeting with promotion hopefuls Watford.
Despite suffering no injuries in Saturday's 2-0 loss to Wigan in their FA Cup semi-final, club physio Bobby Bacic admitted a number of players were fatigued to the maximum.
Attackers Rob Hulse and Shaun Batt, along with midfielder Liam Trotter, all came off the bench at Wembley and could be in line for a starting role next time out.
Trotter could replace Sean St Ledger who twice suffered heavy knocks to his ankle during the cup clash but decided to battle on.
Jackett's only confirmed absentee is regular skipper Paul Robinson who is continuing his rehabilitation from a groin injury in the gym.
The Lions are just three points above the relegation zone but have played two games fewer than a number of their rivals down at the bottom.
Watford will be without suspended defender Marco Cassetti as they look to keep their automatic promotion hopes alive.
But they welcome back Matthew Briggs and Alex Geijo as they bid to finish the season by breaking into the top two places in the npower Championship.
Cassetti was given his marching orders in Saturday's disappointing 3-2 defeat at Peterborough and now serves a one-match ban.
On-loan full-back Briggs was named on the bench at London Road before withdrawing having picked up a groin injury in the pre-match warm-up.
Striker Geijo, meanwhile, missed out altogether due to a knee injury but both are fit for consideration against the Lions.
Otherwise, fit-again midfielder John Eustace is still lacking match fitness after his long-term back injury, while defenders Fitz Hall (hamstring), Nyron Nosworthy (Achilles), Neuton (dislocated shoulder) and Tommie Hoban (ankle) all remain sidelined.
The third-placed Hornets are now six points adrift of Hull with four matches remaining and could see their hopes of a top-two finish disappear completely this week.