Derry gave Trabzonspor a scare in their Europa League second qualifying round first leg before going down 4-2 in Turkey.
Adrian Mierzejewski and Paulo Henrique handed the hosts side a two-goal lead within 15 minutes, only for City to come storming back.
David McDaid pulled one back at the Huseyin Avni Aker Stadium before Patrick Kavanagh drew parity in the 32nd minute.
It had looked like a shock could be on the cards, only for an own goal from captain Barry Molloy to put Derry on the back foot before half-time.
Giray Kacar put Trabzonspor further ahead early in the second half but City continued to threaten, with Ryan McBride firing just wide in injury time as the match finished 4-2 to the hosts.