FC Twente's title hopes suffered a setback with defeat at NEC Nijmegen in the Eredivisie this afternoon.
The visitors were left to rue a 15-minute period either side of half-time when NEC took control of the match.
Lasse Schone opened the scoring from the penalty spot in the 44th minute and goals from Kevin Conboy (50) and Genero Zeefuik (59) put the hosts three up.
Glynor Plet pulled one back for the visitors 13 minutes from time, but it was too little too late.
The only saving grace for Twente, who slipped to third, was title rivals PSV Eindhoven also lost.
NEC carved out the first chance of the game when Krisztian Vadocz found Navarone Foor, who advanced towards the area and fired just wide of the post.
At the other end Luuk de Jong was denied by goalkeeper Gabor Babos when he shot from the right side of the area and Rasmus Bengtsson's header was headed off the line by Ryan Koolwijk.
Bengtsson was then called into action in his customary defensive role, blocking a Schone shot before Foor brought a save out of Nikolay Mihaylov.
Leroy George then fired just wide as NEC started to get a grip of the game, and they made the breakthrough just before the break.
Wout Brama was penalised for a foul on Pavel Cmovs in the area after Zeefuik appeared to get away with a handball and Schone found the corner of the net with the resulting spot-kick.
The hosts doubled the lead five minutes into the second half as Conboy scored with a neat back-heeled finish following Koolwijk's free-kick.
Babos again denied De Jong from close range at the back post, and that miss proved crucial as NEC moved out of sight with a third goal.
Twente were unable to deal with another Koolwijk free-kick and Zeefuik planted a header into the bottom corner.
The visitors applied late pressure in a bid to find a way back into the match and Cmovs was grateful to see his header from an Ola John cross go wide rather than inside his own post.
They pulled one back in the 77th minute when Plet headed home a John corner.
They might have had another only for Nacer Chadli to steer a John centre wide of the right post as NEC held out for the win.