Feyenoord eased to a commanding win over Heracles Almelo but it ultimately mattered little as Ajax retained the title with victory over VVV-Venlo.
Feyenoord knew Ajax needed only a point to become champions for the 31st time and goals by Otman Bakkal, Jerson Cabral, Sekou Cisse and Ruben Schaken saw them into a 4-0 lead before Willy Overtoom scored a consolation.
However, victory moved Feyenoord one spot closer to a Champions League spot, although they must win their final game if they are to keep PSV Eindhoven out of the top two and progress into the competition.
It was all Feyenoord from the outset and they went ahead after 11 minutes.
Ruben Schaken hit a shot across goal which came back off the left post but the rebound fell for Bakkal who slotted home a right-footed shot.
Stefan de Vrij produced a good run from his own penalty area to the Heracles box but his shot lacked real power and Remko Pasveer was not really tested.
With a minute left before half-time Heracles had their first attempt of the game, Ninos Gouriye with a right-footed shot which Erwin Mulder punched clear.
The hosts doubled their lead eight minutes after the break. Karim El Ahmadi passed to Cabral who sent in a left-footed shot to the goalkeeper's right.
Everton Ramos da Silva then hit the bar for the visitors as they briefly threatened but just two minutes later Feyenoord scored their third, Cisse heading home Cabral's corner.
The hosts got their second goal in a minute when straight from kick-off Cabral intercepted and passed to the right of the area, surprising Pasveer with Schaken slotting home from close range.
Overtoom bundled the ball across the line as Heracles pulled one back after 72 minutes and the same player curled the ball against the post six minutes from time.
However, it was Feyenoord's evening as they moved to the brink of Europe's premier club competition.