Mallorca all but secured Primera Division safety with an impressive 4-2 win at relegation-threatened Recreativo Huelva.
The islanders raced into a two-goal lead after just 15 minutes through Jose Manuel Jurado and Juan Arango.
Sisi pulled a goal back for Recre just after the break, but Mallorca went two clear again through Gonzalo Castro 14 minutes from time.
There was another twist shortly afterwards when Javier Camunas bagged a second for the home side and they had the ball in the net once again in the closing stages, but Javi Guerrero's effort was correctly ruled out for handball.
Castro was then sent off for Mallorca and it looked as if the visitors would be forced to endure a few nervous moments in the dying minutes, but Alhassane Keita gave the islanders breathing space with an injury-time strike which sees them move up to a season-high position of ninth.
Although they are not mathematically safe they have now reached the 42-point target that most teams looking to avoid the drop in La Liga equate to safety.
Recre had lost four in a row before this game and it was easy to see why as they went two down with a quarter of an hour.
Jurado opened the scoring following Mallorca's first chance of the match, when he beat a static Recre back-line and slid a low shot past the exposed Asier Riesgo.
And five minutes later, the home side's defence was caught napping once again as the unmarked Arango headed a second goal past Riesgo from Cleber Santana's pinpoint cross.
Jose Luis Marti almost put the visitors out of sight just short of the half-hour mark, but was just off target with a powerful drive.
Three minutes later, Recre threatened for the first time in the match, but Mallorca goalkeeper Dudu Aouate reacted superbly to keep out Guerrero's cross shot.
Sisi should have pulled a goal back shortly afterwards, but inexplicably failed to make decent contact from just a few yards out and Mallorca cleared.
At the other end, Aritz Aduriz missed a good chance to score a third for Manzano's side just before the break.
The islanders will have been happy to go in two goals ahead at the break, but they saw their advantage sliced in half shortly after the interval, when Sisi pounced on a loose ball that Nunes and Aouate both left for each other.
There were chances for both sides after that, but Castro looked to have sealed it for Mallorca when he played a one-two with Jurado and finished with aplomb with 14 minutes left.
Back came Recre, though, when Camunas drilled an angled shot past Aouate to reduce the deficit once again.
That goal lifted the Andalusians and they had the ball in the net once more soon afterwards, but Guerrero clearly handled and was penalised.
There was a glimmer of hope for the home side in the dying minutes, though, after Castro was sent off following a second yellow card.
But Keita beat two mean and fired past Riesgo at the near post to condemn the locals to another miserable afternoon and leave them second to bottom, four points adrift of safety.