Under-pressure Sampdoria coach Walter Mazzarri received a much-needed boost this evening as his side romped to a convincing home victory over Serie A basement boys Reggina.
Daniele Dessena opened the scoring in the second minute and doubled his team's advantage on the half-hour mark after Carlos Adrian Valdez had been dismissed. Gennaro Delvecchio made it three to virtually wrap up the points eight minutes before the interval.
And Samp did not ease up after the break, netting further goals through Guido Marilungo and Giampaolo Pazzini in the first seven minutes of the second half to seal a massive win.
Last weekend's 3-1 defeat by city rivals Genoa saw the heat turned up on former Reggina boss Mazzarri, who looks set to leave Samp at the end of the season.
Blucerchiati general manager Beppe Marotta has confirmed the coach's future depends on how well the club end the campaign, with much seemingly hinging on the outcome of next week's Coppa Italia final against Lazio.
But things could not have gone much better for his troops tonight, with Dessena slotting into the bottom-right corner of Christian Puggioni's net with less than two minutes on the clock.
Reggina did not crumble, and mustered a couple of good chances to get back on level terms.
First Edgar Barreto crossed from the right for Carlos Carmona, whose header was well saved by Luca Castellazzi, and then Franco Brienza saw his 25-yard free-kick also kept out by the home goalkeeper.
The visitors suffered a body blow in the 19th minute when Valdez saw red for a last-ditch tackle on Pazzini, who was bursting through towards the Amaranto goal.
Samp took only 12 minutes to make the extra man count, going 2-0 up in the 31st minute. Dessena was again the man on target, firing into the bottom-right corner.
Reto Ziegler's free-kick then found Delvecchio, who directed his header into the top-right corner to make it 3-0 in the 37th minute.
Mazzarri's side could even have grabbed a fourth before half-time had Pazzini made a better connection to Marco Padalino's right-wing cross.
Goal number four did arrive in the opening moments of the second period, however. Puggioni pulled off a brilliant save from Pazzini but Padalino latched onto the rebound and crossed onto the head of Marilungo.
Puggioni again had to be alert four minutes later to get his body in the way of a Padalino effort, but he was powerless to prevent the fifth in the 52nd minute. He kept out Marilungo's initial 20-yard effort, but Pazzini was following up and made no mistake.
Bernardo Corradi tried his luck from 25 yards just after the hour mark in a bid to give the visiting fans something to cheer about, but the ball flew harmlessly wide to the left.
Corradi then had a shout for a penalty when Samp defender Daniele Gastaldello looked to have pulled his shirt, but the referee was not convinced.
Reggina kept on battling in a bid to get on the scoresheet - Castellazzi comfortably catching a Brienza header from Corradi's cross and Daniele Adejo's header from Andrea Costa's corner cleared off the line by Daniele Gastaldello - but it was not to be.
The visitors remain bottom of the standings, three points behind fourth-bottom Torino with three games remaining. Samp, meanwhile, climb a place to 12th.