Wycombe manager Gareth Ainsworth will be without Charles Dunne again for the Johnstone's Paint Trophy tie with Bristol City.
The on-loan Blackpool full-back was sent off for the second time in as many games in the 2-1 defeat to Burton. Dunne was making his first start since serving a three-match ban for a straight red against Oxford. His two yellow cards on Saturday mean he will miss two more matches.
Top scorer Dean Morgan, Leon Johnson (both thigh) are both doubtful and Steven Craig remains sidelined due to a viral infection.
The Blues reached the second round with a 2-0 victory at Exeter and progressed to the southern section quarter-finals last season before losing to Yeovil.
Bristol City pair Aden Flint and Louis Carey remain doubtful for the clash.
Flint is nursing an ongoing knee injury and could be replaced by Mitch Brundle, who would make his first start, while Carey is struggling with a viral infection.
Goalkeeper Frank Fielding is expected to return in place of Elliot Parish, while on-loan Brighton defender Lewis Dunk is in line for his debut.
Sean O'Driscoll's side have yet to taste league success, but earned bragging rights and a place in the second round of the Johnstone's Paint Trophy with a 2-1 win over rivals Bristol Rovers.