Michael Laudrup expects Valencia to be a completely different proposition from their September meeting when the sides clash in the Europa League at the Liberty Stadium.
Swansea stunned the Spanish club and claimed one of the most famous wins in their history when they secured a 3-0 victory at the Mestalla in the opening round of Group A fixtures.
The win came during a miserable start to the season for Los Che and heaped pressure on coach Miroslav Djukic.
Their form initially recovered, and three consecutive Europa League wins mean they have already reached the knockout stages and sit top of Group A.
However, they have lost four of their last six games in the Primera Division and lie 11th in the table.
The club have also recently appointed a new sporting director to work with Djukic, although Francisco Rufete has not made the trip to Wales.
But, despite recent form, Swans boss Laudrup believes the freedom of having already nailed down a place in the last 32 will mean it is a very different Valencia team come Thursday evening.
He said: "When we played them at the Mestalla, it was under special circumstances. They had come off the back of three defeats in the league.
"Obviously it was special for this club to beat one of the big teams in Spain, people here could tell you that.
"But then they came back on track, they won a few games.
"They have lost a few in the last few weeks, but it will be different to the game there because they already qualified, they don't have to think about this competition before February so it changes things.
"It was a great win because of the reputation of Valencia.
"They have played in the Champions League and reached two finals last 12 years ago.
"We played a great game out there, but we have to remember they played 80 minutes with one man less (after Adil Rami's red card) and in difficult circumstances because of the atmosphere.
"We played well, it was a good game, and it would be nice to repeat. it but it won't be easy."ut it."
Laudrup hopes to have winger Pablo Hernandez back against his former club.
Meanwhile, Valencia coach Djukic insists he is still in charge despite Rufete's arrival.
"If I did not have freedom I would not be here, that's obvious," he said. "I still think I am the most important person with the most authority inside the dressing room.
"It is important this continued, also what I have seen in the press in the last few days about the recording, I don't see this as negative. All the big clubs have it and it is important for our structure to see how we can improve. I do not see anything suspicious about this.
"We discussed everything and we decided to record training to see what we may be missing and look at our methods, I feel it is a very positive thing.
"It just improves the club. In most clubs if a manager leaves there is nothing left for the new coach. If we keep everything it can be a help to our future coaches. As I have said all the big clubs do this, they record all their training."