Falkirk will have David McCracken available to face Hamilton.
The defender has recovered from the thigh injury which saw him replaced at half-time in the 1-0 win over Livingston last weekend.
Missing for the Bairns will be Thomas Grant, who has been suffering from a virus.
Technical director Alex Smith hopes Falkirk can break their duck against their opponents.
Smith said: "We have lost twice to Hamilton this season so we would like to put that right. A victory would really get us into the mix at the top of the table as well so there is plenty of motivation to win."
The Accies, who have bounced back to form recently with two wins in a row, have Darian MacKinnon back in their ranks after suspension.
A groin injury keeps player/manager Alex Neil absent and a knee problem sees Jonathan Routledge remain out.
Manager Alex Neil said: "This is really crucial period as we play Falkirk and then Dundee with Falkirk then hosting Dundee in a fortnight. Whoever comes through this period the best will have done themselves a huge favour.
"We are playing well just now and hopefully we will keep that going at the Falkirk Stadium."