Cowdenbeath will miss the goal threat of Jamie Stevenson in their Ramdens Cup Fife Derby with Dunfermline after his sending off in a pre-season friendly.
Blue Brazil boss Colin Cameron brought former Rangers striker Kane Hemmings back to the club on Thursday evening after a successful loan spell last season and he joins fellow new recruits Nat Wedderburn, Jordan Morton and Andy Russell in his squad to face the Pars.
Cameron said: "This is afantastic game to open the season as our games with Dunfermline always have a bit of spice attached to them. It will be a tough tie to win but we have looked good in pre-season."
Dunfermline miss the suspended Stephen Husband, however their squad should be boosted by the return of Andy Geggan and Ryan Wallace after injury.
Alan Smith remains out with a leg knock, with Jefferies hoping to have completed a loan deal ahead of kick-off.
Jefferies said: "We started our league season last year with a 4-0 win at Central Park and it would be great to do something like that again.
"Unfortunately the financial situation at the club means that we are a very different side now however a win in this game would be a great boost for this campaign."