Exeter are sweating on the fitness of strike duo Sam Parkin and John O'Flynn for the Devon derby with Plymouth.
The pair both missed last weekend's 2-1 win over Fleetwood with hamstring problems and Tisdale is expected to hand them fitness tests before the early kick-off.
If they fail to make it then Jamie Reid could partner Alan Gow upfront while in midfield the City boss hopes Matt Oakley is fit to play having picked up a knock in Saturday's victory.
Scot Bennett was the Grecians' goalscoring hero last weekend having been moved upfront from centre back and it remains unclear where the youth product, who can also play in midfield, will feature.
Plymouth full-back Durrell Berry is available again.
The defender missed the 0-0 draw with Accrington on Saturday with a virus and he will have to fight for his place against their biggest rivals with Curtis Nelson who stood in at Home Park.
Experienced defender Paul Wotton made his first start since the opening day last weekend and his experience could see him retain his place ahead of Neal Trotman against the Grecians.
Young striker Tyler Harvey looks set to be involved again after two goals in a Devon Bowl victory in midweek but he may have to make do with a place in the Argyle bench.