Exeter could be without five first-teamers when they take on AFC Wimbledon.
Youth-team graduates Scot Bennett and Jordan Moore-Taylor, who have started the Grecians' opening three games, both sustained knee injuries in Saturday's goalless draw with Mansfield and will be assessed.
If the duo fail to make it then Tommy Doherty and Aaron Dawson look certain to be recalled.
Matt Oakley is yet to feature this season while Paul Tisdale is hoping Alan Gow will overcome the dead leg he suffered in their 2-0 Capital One Cup defeat against QPR earlier this month. Centre-back Pat Baldwin could also be missing as he awaits news of the birth of his first child, due on Saturday.
AFC Wimbledon boss Neal Ardley has a virtually full-strength squad.
Centre-half Will Antwi is the only absentee as he recovers from a hernia op, and he should be back in contention within the next couple of weeks.
Fellow defender Rhys Weston is set to be on the bench again following his recent switch to Kingsmeadow with Ardley unlikely to tinker with the side which beat Wycombe 1-0 last weekend.
Andy Frampton (dead leg) and Michael Smith (ankle) shrugged off knocks to face Wanderers and should keep their places, while winger Kevin Saint-Luce could be added to the squad after recovering from a hamstring injury.