Hamilton welcome back midfielder Gary Fisher after a two-game suspension as skipper Alex Neil makes his home debut as interim player/manager against bottom-of-the-table Airdrie.
But a knee injury is likely to keep Neil away from the action and striker Kieran Millar is also missing due to a knee problem.
Neil said: ``When we played Airdrie in our last game here at New Douglas Park we put on a great display and won 3-0 and I scored a goal which does not happen too often.
``I thought we were worthy winners in my first game in charge at East End Park on Saturday when we beat Dunfermline 3-2. I enjoyed that experience but that is probably because we won and hopefully I will feel the same after this game.''
Airdrie will be without defender Grant Evans through suspension after he was dismissed in Saturday's 5-2 defeat to Morton.
David Lilley returns after his own ban but Jordan Kirkpatrick and John Boyle are out with knee injuries.
Manager Jimmy Boyle said: ``Defence has been our weak point all season and it was again at Cappielow on Saturday.
``We will keep working to get it right regardless of the stage of the season. It has been a tough season for us in terms of results but hopefully our young players will be better for the experience.
``We are going to Hamilton and looking to make sure they know they have been in a game.''