Leeds' leading goalscorer Luciano Becchio is battling to be fit to face Bolton at Elland Road but defender Aidy White is suspended.
Striker Becchio missed Saturday's 2-0 defeat at Hull due to a thigh strain, meaning Davide Somma made his first start for the club in 19 months following a serious knee injury.
White received his fifth booking of the season at the KC Stadium and sits out an automatic one-game ban.
Forward Ross McCormack also returned to the starting line-up at Hull and manager Neil Warnock must decide which combination to utilise against Bolton.
Warnock made five changes against the Tigers, opting to start with three central defenders, while White and Sam Byram operated as wing-backs.
Striker El-Hadji Diouf and on-loan winger Jerome Thomas were not included in the squad on Saturday and will be hoping to feature.
Leeds have slipped to successive league defeats at Nottingham Forest and Hull and are now five points adrift of the play-off places in ninth.
Bolton boss Dougie Freedman will assess a handful of knocks among his squad before the New Year's Day trip.
David Ngog missed Saturday's 3-1 victory over Birmingham at the Reebok Stadium with a twisted ankle and fellow forward Benik Afobe was restricted to a late cameo from the bench due to a slight hamstring problem.
Republic of Ireland international Keith Andrews started and played through the pain of an Achilles complaint.
Fellow midfielder Mark Davies remains out with a shoulder injury, while defender Matt Mills (thigh) is still unavailable.
Freedman has been boosted by the news that Stuart Holden is closing in on a first-team return, but the USA midfielder will stay sidelined until the end of January alongside fellow long-term knee injury victims Josh Vela and David Wheater.