Fiorentina's Romania striker Adrian Mutu has dislocated his elbow training with the national squad and will miss Wednesday's friendly with Latvia.
Romania midfielder Mirel Radoi will miss the rest of Euro 2008 after sustaining a serious head injury against Italy.
Holland coach Marco van Basten will urge his players to give their all in their last Group C outing, even though a defeat against Romania on Tuesday would see pre-tournament favourites France and Italy eliminated from Euro 2008.
Romanian media on Saturday both praised and damned Adrian Mutu after scoring a goal and missing a penalty in a 1-1 draw against Italy at Euro 2008 -- but he won backing from former great Gheorghe Hagi.
Italy coach Roberto Donadoni felt his team were superior to Romania on Friday, but also admitted the Azzurri were fortunate to be alive in the tournament after several refereeing decisions went against them.
Romania striker Ciprian Marica has been ruled out of their Euro 2008 match against world champions Italy on Friday after failing to recover in time from a head injury, a team spokesman said.
Romania fullback Cosmin Contra said victory over the Netherlands was still his team's best route to the Euro 2008 quarter-finals, no matter what happened in their next group game against Italy on Friday.
Romania captain Cristian Chivu said his team will make things very difficult for world champions Italy when they meet at Euro 2008 on Friday.
Ciprian Marica was rushed to hospital with a head injury after colliding with fellow Romania striker Marius Niculae in training on Tuesday.
France coach Raymond Domenech believes Group C will go down to the wire after seeing his side draw 0-0 against Romania in their Euro 2008 opener.