Juventus opened up a five-point lead at the Serie A summit Saturday evening with a 2-0 win over Fiorentina while second-placed Napoli could only manage a 1-1 draw at Lazio.
Juve boss Antonio Conte had played down talk of a fierce rivalry between Turin and Florence and there was precious little evidence of competition on the pitch as Vucinic was left unchallenged to slam home the opener.
Matri lost his boot when swinging at Arturo Vidal's canny pass but his socked foot guaranteed Juve all three points before what turned out to be an insipid second half.
Napoli secured a point in the evening's later game thanks to Hugo Campagnaro's spectacular 87th-minute equalizer at the Stadio Olimpico.
Campagnaro met Omar El Kaddouri's corner with an acrobatic scissor-kick to cancel out Sergio Floccari's breakaway goal in the 11th minute.
Juventus owned the first half of its game, as Stevan Jovetic let rip with a fine left-footed effort inside 60 seconds.
Andrea Pirlo was back to his imperious best tonight, with a series of deft balls forward to Vidal and Claudio Marchisio inspiring gasps from the bumper crowd.
Juve's first shot on goal came through Marchisio, who dribbled to the edge of the area before directing an effort just wide, before Emiliano Viviano was called into action.
With Vucinic free to do as he pleased at the end of an attractive passing move, the Montenegrin rifled the ball against Fiorentina's goalkeeper.
Vucinic's compatriot Jovetic soon warmed Gianluigi Buffon's palms on the turn but it would be Juve that made the breakthrough.
With 20 minutes played, Vucinic unleashed a furious right-footed drive that streaked past a stranded Viviano and into the net.
A chance for a quickfire second went begging when Vucinic failed to tuck the ball away when Gonzalo Rodriguez offered it to him on a plate at the edge of his area
Juve would give itself a significant advantage going into the break, though, as Matri stole onto a Vidal pass to steer the ball past Viviano.
Replays showed the former Cagliari man's boot had flown off before he scored with his sock.
Pirlo went close himself when play resumed, just before Marchisio and Federico Peluso picked up the bookings that will keep them out of next week's trip to Roma.
It was then time for Sebastian Giovinco to make an entrance when Vucinic called to be replaced after crashing to the ground and hurting his knee.
Matri shrugged off the lull in action to burst onto a Stephan Lichtsteiner pass and drag the ball just wide of a post.
Fiorentina substitute Mounir El Hamdaoui got Buffon working again when he twisted and turned to beat Peluso and Giovinco promptly drew a low save from Viviano at the other end.
But after the high-tempo escapades of the first 45 minutes, the second half was a limp affair and not even Paul Pogba could liven things up with one of his trademark long-range screamers.
The Frenchman looked up and shaped himself to shoot but opted instead to pass sideways to Marchisio, who could not quite dig out one last meaningful effort on the half-volley.
Information from Press Association was used in this report.