Juventus may well be forced to take on neighbours Torino this weekend without South American duo Martin Caceres and Arturo Vidal as both are suffering with injury.
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The first Turin derby of the season is this Sunday but the Bianconeri face a double blow as the players both pulled up during a training session on Tuesday.
Uruguayan defender Caceres has been diagnosed with a sprain to his left ankle, with a test showing "a slight distraction of the ankle ligament" according to an official club statement. He will be further assessed in the coming days but is unlikely to recover before the weekend.
Vidal, meanwhile, is struggling with muscle fatigue in his thigh and the Chilean midfielder has looked increasingly weary in recent matches with many speculating he would have been rested against Torino even before suffering this problem.
Former Manchester United player Paul Pogba is a likely replacement, with Juve keen to give key midfielder Vidal every chance of being available for their Champions League meeting with Shakhtar Donetsk next week.