Defending champions Juventus came from behind to extend their perfect start to the season with a comfortable 3-1 win at Genoa.
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Ciro Immobile put the home side in front in the 18th minute and they missed numerous chances to double their lead before Emanuele Giaccherini brought the Bianconeri level after an hour.
Mirko Vucinic and Kwadwo Asamoah added a second and a third to make it three wins out of three for Juve, who will travel to face Chelsea in the Champions League on Wednesday in high spirits.
Inter Milan picked up their second away win of the season, beating Torino 2-0 thanks to goals by Diego Milito and Antonio Cassano.
Milito put the Nerazzurri ahead in the first half and they resisted a spell of pressure from the home side before Cassano added the second in the last ten minutes. The win lifts Inter into the top five, leaving Torino beaten for the first time this season.
Lazio maintained their 100% winning start to the Serie A season after a comfortable 3-1 victory against Chievo at the Stadio Marcantonio Bentegodi.
Hernanes was the star of the show scoring twice in either half while he also set up Miroslav Klose for his strike as Vladimir Petkovic's side registered their third league win in a row. Sergio Pellissier netted a late penalty for the hosts, who tasted defeat for the second game running after last week's 2-0 reverse at Bologna.
Napoli also maintained a perfect start with a 3-1 win over Parma at the Stadio San Paolo.
Walter Mazzarri's men are well fancied by some to mount a serious title challenge this campaign and have backed that up so far, winning all three of their games.
They were in control from the moment Edison Cavani netted a third-minute penalty and, with Goran Pandev and Lorenzo Insigne also on target, Marco Parolo's strike was rendered worthless.
Newly-promoted Sampdoria, another team to have won all their games to date, claimed another victory as a Maxi Lopez double helped them see off Pescara 3-2.
The Argentinian gave his side the lead, which was doubled by Marcelo Estigarribia in the second period. Mervan Celik pulled a goal back for the hosts with 15 minutes left before Lopez netted again to extend his side's advantage, as Gianluca Caprari scored a late consolation.
Bologna came from two goals down to claim their first points of the season with a 3-2 victory over shellshocked Roma at the Stadio Olimpico.
The Giallorossi looked to be cruising when Alessandro Florenzi and Erik Lamella struck in the first 15 minutes, but two goals in as many second-half minutes from Alberto Gilardino and Alessandro Diamanti brought Bologna back on level terms.
There was then one final twist in the dying seconds when Gilardino grabbed his second of the match after an embarrassing mix-up in the Roma defence.
Udinese were two goals in front after just five minutes but were held to a 2-2 draw by Siena, who hit back with a pair of second-half strikes following Andrea Lazzari's red card.
Dusan Basta put the visitors ahead after three minutes with a powerful effort, with Antonio Di Natale doubling the lead soon after from close range, bBut the game changed when Lazzari received a second caution after 52 minutes as first Emanuele Calaio and then Ze Eduardo, with a 77th-minute penalty, scored for Siena.
Goals in each half from Steven Jovetic and Luca Toni handed Fiorentina all three points in a 2-0 win against Catania at the Stadio Artemi Franchi.
Montenegro forward Jovetic put the hosts ahead just before half-time and veteran striker Toni sealed victory moments after stepping off the bench. The victory was Fiorentina's second in three matches, with Catania suffering their first defeat of the new campaign.