Wigan are trying to prevent losing three more of their top players on free transfers next year after two departed this summer in the same fashion.
Franco Di Santo, Maynor Figueroa and Antolin Alcaraz are all out of contract at the end of the season and could walk away from the club without Wigan receiving a fee.
Roberto Martinez lost Hugo Rodallega, who joined Fulham, and Mohamed Diame, who went to West Ham, this summer after they failed to agree new deals at the DW Stadium.
Now Wigan hope to persuade striker Di Santo and defenders Figueroa and Alcaraz to commit their futures to the club after having been in discussions for some time.
"We have been talking with some players who are coming up to the end of their contracts now for 18 months, and that will continue," chief executive Jonathan Jackson told the Wigan Evening Post.
"In modern football, it's not important just to bring top players in - you have to keep hold of the top players you already have. That doesn't mean just preventing them from being transferred to another team. It means securing their contracts so they can't walk away as free agents.
"We want to keep all of our quality players here. But it's not always possible, as we saw last season."
Di Santo is in the best form of his Wigan career after scoring five goals in eight games while Figueroa and Alcaraz were vital figures in Martinez's back three when they won seven of their final nine games last season.