United close gap, Spurs stifled
Bolton's Hungarian goalkeeper Adam Bogdan denied Wayne Rooney from the spot at Old Trafford.
But Paul Scholes scored on his first start since the final day of last season to put Man Utd ahead.
Danny Welbeck scored United's second and Michael Carrick completed the 3-0 win with a rare goal.
Tottenham have been flying high of late but were stunned when Steven Fletcher put Wolves ahead at White Hart Lane.
Spurs equalised through Luka Modric but were unable to push on and find a winner.
Fernando Torres hit the bar but Frank Lampard was on hand to score the rebound, which proved Chelsea's matchwinner against a spirited Sunderland.
Sunderland ran Chelsea close, but Andre Villas-Boas' side condemned Martin O'Neill to his first defeat as Sunderland manager.
There were plenty of dominant aerial players on show in Liverpool v Stoke and both sides managed to nullify each other.
Andy Carroll came off the bench but was again unable to find the net for the Merseysiders. He's scored just two in 18 games this season.
Darron Gibson made his Everton debut against Aston Villa, but it Was Darren Bent who struck, putting the hosts into the lead.
But Toffees substute Victor Anichebe snatched an equaliser for the visitors - his second goal in the West Midlands in as many weeks.
Struggling Blackburn got off to a miserable start against Fulham when Yakubu was sent off early on for a bad challenge on Danny Murphy.
Morten Gamst Pedersen fired Blackburn's ten men into a 1-0 lead with a well-taken free-kick.
Damien Duff scored what proved merely a consolation for Fulham, on his return to one of his former clubs.
Mauro Formica rounded off an impressive 3-1 victory for Rovers.
Steve Morison was on the scoresheet for the ninth time this season, netting Norwich's winner against West Brom.