Kolbeinn Sigthorsson scored five goals as AZ Alkmaar boosted their European hopes with a thumping Eredivisie victory over second-bottom VVV-Venlo.
Sigthorsson bagged a hat-trick within the first half-hour to virtually make the points safe before Ahmed Musa pulled one back after 37 minutes.
But any hopes of a comeback were quickly dashed after the break. Sigthorsson was on target again in the 47th minute and rounded off the scoring after international team-mate Johann Berg Gudmundsson had helped himself to AZ's fifth.
Genero Zeefuik spared PSV Eindhoven's blushes as he scored deep into injury time to complete a comeback against nine-man Eredivisie basement dwellers Willem II.
The win puts PSV four points clear at the top of the table ahead of FC Twente's match with Feyenoord, but it did not come easy for an unconvincing PSV side. Bart Biemans gave the visitors a shock 17th minute lead, and that would last into the second half before Ola Toivonen levelled.
Willem then had Denis Halilovic sent off for a second bookable offence and Veli Lampi was shown a straight red, but even against nine men PSV struggled until Zeefuik popped up three minutes into time added on to score a winner.
Vitesse Arnhem were also among the goals as they came from behind to trounce Roda JC 5-2.
Marco van Ginkel netted twice with Nemanja Matic, Jordi Lopez and Haruna Babangida also finding the target as the home side produced a stylish display at Gelredome.
Mads Junker and Jimmy Hempte scored for Roda, but defeat prevented them from climbing into the top four.
The clash between De Graafschap and FC Utrecht had to be postponed due to a frozen pitch at De Vijverberg and will now be played on Sunday instead.