Park, who started last season's Champions League final against Barcelona, missed training after contracting the virus, leaving Sir Alex Ferguson little choice but to rule the South Korean out. Better news for United is that Evra has recovered from a similar illness.
"Ji-Sung has a virus," said the United boss. "Patrice Evra had it at the weekend. After the Stoke game he felt a bit uneasy - he was in bed on Sunday and didn't come to training, but he came in for a bit yesterday, came in today and he should be alright."
Meanwhile, Manchester derby hero Michael Owen is expected to recover from a groin strain that forced him out of training.
"Michael should be alright for tomorrow," Ferguson said. "He had a tight groin in training yesterday, nothing serious. But obviously for the game tomorrow we didn't want to be pushing that. Other than that everyone's fit."