LONDON -- Chelsea lost for the first time this season in the Premier League, beaten 2-0 at Aston Villa on Sunday and missing a chance to return to first place.
Defender Zat Knight had a goal in 47th minute and Gabriel Agbonlahor added another in the 88th as Chelsea desperately tried to even the score.
"The reaction we had in the last 20 minutes, we should score a goal," Chelsea coach Jose Mourinho said.
Arsenal defeated Portsmouth 3-1 despite playing with 10 men for most of the second half. Emmanuel Adebayor, Cesc Fabregas and Tomas Rosicky scored for Arsenal. Kanu scored in the 60th minute for Portsmouth.
Chelsea trails leader Liverpool on goal difference as one of four teams with 10 points. The others are Everton and Arsenal. Liverpool has played one fewer game. Manchester City was a point back in fifth after losing 1-0 at Blackburn in Sunday's other game.
Arsenal's Philippe Senderos was sent off for pulling back Nwankwo Kanu in the 49th minute when the former Arsenal forward was running through the defense.
Portsmouth goalkeeper David James brought down Robin Van Persie in the area in the eighth minute, and Adebayor sent the penalty kick low to James' right. Fabregas made it 2-0 in the 35th and Rosicky increased the lead in the 59th. Kanu scored seconds later when the ball rebounded off his leg as he tried to control it with his back to goal.
MILAN, Italy -- Juventus needed a late winner to beat Cagliari 3-2 in the Italian league, and AS Roma cruised to a 3-0 victory over Siena.
Giorgio Chiellini scored with a diving header in the 90th minute after Pasquale Foggia had twice tied the score for Cagliari with penalty kicks. David Trezeguet and Alessandro Del Piero scored Juve's other second-half goals.
Alberto Aquilani scored his second goal of the season with a swerving shot in the 17th minute to put Roma ahead 1-0, and Ludovic Giuly and Francesco Totti added two more in the final eight minutes.
Juventus and Roma remain unbeaten after two games. Newly promoted Napoli routed Udinese 5-0. Former Juventus forward Marcelo Zalayeta scored twice and Maurizio Domizzi, Ivan Lavezzi and Roberto Carlos Sosa added the others.
AMSTERDAM, Netherlands -- Ajax dropped its first points in the Dutch league after being held to a 2-2 tie by FC Groningen.
Ajax, which was knocked out of the Champions League on Wednesday, took the lead when Luis Suarez scored in the 33rd minute. Groningen then got two goals from Marcus Berg before Klaas Jan Huntelaar scored the final goal for Ajax in the 83rd.
Vitesse Arnhem maintained its perfect start with a 1-0 win over NEC Nijmegen. Harrie Gommans scored the only goal.
GLASGOW, Scotland -- Celtic scored three second-half goals to beat Inverness Caledonian Thistle 5-1 and move within two points of Scottish Premier League leader Rangers.
Mark Brown, Scott McDonald, Jan Vennegoor of Hesselink and Stephen McManus scored for Celtic, with Franco Miranda adding an own-goal. Miranda also scored for Inverness.