Injuries to skipper Dejan Stefanovic and Matt Taylor have left Portsmouth in crisis ahead of Wednesday's Premiership trip to Liverpool.
As a result, manager Harry Redknapp is considering a recall for defender Andy Griffin from his loan spell at Stoke to provide vital cover at the back.
Stefanovic entered a Sheffield hospital today for knee surgery after defying doctor's orders and playing for Pompey in the 1-0 defeat at Newcastle.
Taylor, omitted from the starting line-up after a virus, replaced Stefanovic at half-time but is a huge doubt for the Anfield visit after hurting his back when landing awkwardly during yesterday's game.
He had to play on in agony during the last 15 minutes after Pompey used all their permitted three substitutes at St James' Park.
The former England under-21 international had only just been given the all-clear by medics to rejoin the squad after a head injury - sustained in an accidental clash with team-mate Sol Campbell more than two weeks ago - which left him feeling ill.
His absence could leave Redknapp's team - already missing right back Glen Johnson (thigh), plus strikers Andy Cole (Achilles) and Lomana LuaLua (ankle) - without a recognised left-back.
So Griffin is poised to be recalled from Stoke and asked to plug the gap at Liverpool.
He is into a third month on loan having not even figured as a substitute for Pompey this season.
Redknapp admitted: 'Matty is struggling. He's trapped a nerve in his back. It means I haven't got a left-back on my books now. Dejan is having an operation.
'I've got Andy Griffin away on loan at Stoke, so I'll probably have to recall him for Liverpool.'