Roma will attempt to join Manchester United in the history books when they take on the MLS All Stars this summer.
United have had success in two of the league's annual all-star games over the past few years, winning by a combined score of 9-2.
However, the All Stars have not been defeated by another club outside of the United States since the MLS adopted its current all-star game format a decade ago.
The likes of Celtic, West Ham, Fulham and Chelsea all failed in their attempts to match the Red Devils' heroics, with the Blues going down 3-2 last summer.
"We're thrilled to be able to bring a club as historic as Roma outside of Europe and play in the U.S.,'' Roma board member Mark Pannes said on Thursday.
The game will be played at Sporting Park, the home of MLS club Sporting Kansas City, on July 31.
"We think this format is tremendous, when you can take the best players in MLS and play one of the best clubs from Europe,'' Pannes said. "It's highly challenging.''
Roma, founded in 1927, became the first Serie A club to be owned by foreigners when a four-man group from the United States bought a majority interest in August 2011.
"Playing in the MLS All-Star game fits in perfectly with our initiatives in the United States,'' Roma president James Pallotta said. "Major League Soccer has done a great job building its all-star game into a top-tier event and we're proud to participate.''
MLS president Mark Abbott is delighted that Roma have decided to sign up, and feels the Italian outfit are the perfect fit.
"I can't think of a better club to join us here. They're one of the most successful and popular clubs in Italy, they have tremendous players and some household names,'' said MLS president Mark Abbott said. "We think the format makes this game very compelling and very entertaining, and to have clubs from different leagues around the world is perfect for us.''