Fulham will be without striker Dimitar Berbatov when they take on Premier League champions Manchester City at Craven Cottage on Saturday.
Berbatov, 31, will be out for two weeks with a hip problem, Fulham manager Martin Jol said.
It is a blow for the Londoners after the Bulgarian, who arrived from Manchester United on deadline day, made an explosive start to life at Craven Cottage.
"Unfortunately Dimitar is injured now and can't play on Saturday, so that is the disappointing thing," Jol said. "He will be out for the next two weeks.
"In his training session, he was looking good as usual, and then on his final shot he felt something and he had to go in and stop training.
"It appears he had not a tear but a sort of problem with his hip and upper thigh, so we couldn't take the risk to involve him against City."
However, there was better news for Fulham when it emerged that an injury to Mahamadou Diarra is not as severe as first feared.
"Diarra had a minor operation but he will still be out for the next four weeks at least," Jol said. "They removed a little piece of bone from his knee and that was it, so that was pleasing. There was not a lot of damage.
"If there had been more damage with his knee with his ligaments or his cruciate then he could have been out for a lot longer, but it's still four weeks."