Emelec of Ecuador clinched a valuable win in Paraguay by defeating Olimpia 1-0 in the first leg of the Copa Sudamericana's second round.
Argentinian defender Cristian Nasuti headed a Polo Wila free-kick into the back of the net for the only goal of the game. The return match will be played on September 19 in Guayaquil.
Ecuadorian giants Barcelona gained an important point from their trip to Chile with a 0-0 draw with Cobreloa.
However, they will feel they should have won the game after Narciso Mina fired a 39th-minute penalty wide after he was fouled by Sebastian Roco.
Midfielder Luis Caicedo will miss the return game for Barcelona after he was shown a red card following a foul on Jose Perez.
In Colombia, hosts Envigado drew 1-1 with Uruguay's Liverpool.
Yulian Mejia put the home team ahead in the 22nd minute but midfielder Neider Morantes was shown red in the 82nd and Liverpool made the most of their numerical advantage as Rodrigo Aguirre equalised in the closing stages.