Valencia let a lead slip away for the fourth consecutive home game as Arouna Kone's second-half strike earned local rivals Levante a 1-1 draw at the Mestalla.
Jonas Goncalves rounded off a fine team move to give the hosts the lead 10 minutes before half-time, but Levante were level eight minutes after the break as Valdo headed Jose Barkero's cross into the path of the Ivorian who rifled home his 11th league goal of the season.
Both sides had great chances to win the game in the final 10 minutes as Kone stabbed Pedro Botelho's cross inches wide before substitute Paco Alcacer headed straight at Gustavo Munua with the goal at his mercy.
Diego scored on his first start for seven weeks as Atletico Madrid cruised to a comfortable 3-0 win over Getafe.
Eduardo Salvio put the hosts in front midway through the first-half as he brilliantly looped a header over Miguel Angel Moya from Filipe Luis' cross.
Diego then made it two just after the hour mark as his initial header off the bar rebounded kindly for him to tap home at the second attempt, and Radamel Falcao wrapped up the three points 13 minutes from time with another calm finish from Juanfran's cross.
Atletico are now a point outside the Europa League places and five off the Champions League.
Villarreal barely helped their relegation fight following a forgettable 0-0 draw against European hopefuls Espanyol at El Madrigal.
Both sides had the ball in the net, but both were ruled out for questionable fouls. Marco Ruben thought he had scored for the hosts in the first half when he poked in after Espanyol goalkeeper Francisco Casilla fumbled only for the referee to whistle.
Villarreal then thought they had a penalty for a foul on Borja Valero before Espanyol were denied when Raul Rodriguez's finish was ruled out for an earlier foul on Diego Lopez. The draw left Villarreal four points above the relegation zone while Espanyol have a two-point gap to bridge behind the Europa League places.
Real Sociedad returned to winning ways in emphatic style with a thumping 4-0 home victory over Rayo Vallecano that could prove vital to their hopes of staying up.
A run of four defeats in five games had seen Sociedad slip ever closer to the relegation zone but they earned a priceless three points against mid-table Rayo thanks to goals from Imanol Agirretxe, David Zurutuza, Antoine Griezmann and Carlos Vela.
The victory lifts Sociedad eight points clear of the bottom three and one point behind Rayo.