Manchester United's reward for beating Manchester City in the FA Cup was a Fourth Round trip to Anfield to take on Liverpool.
The game will be the first meeting of the two sides since the controversial clash in October when Liverpool forward Luis Suarez racially abused United defender Patrice Evra. Liverpool accepted an eight-match ban for the Uruguayan over the incident earlier this month.
Players from United and Liverpool reacted positively to the draw on Twitter.
United defender Rio Ferdinand Tweeted: ''Liverpool away...what a tie! Great game for the £FaCup + our fans! Let's av iiiiiit! Roll on the 4th round.''
Reds midfielder Charlie Adam added: ''Great draw man united @ home that's the FA cup.''
QPR will host west London neighbours Chelsea if they can overcome the MK Dons in a replay at Loftus Road.
Chelsea captain John Terry could make a first return to the ground since he was accused of racially abusing Rangers defender Anton Ferdinand, a matter which has become the subject of a criminal case and an accusation which he strenuously denies.
As well as Liverpool versus Manchester United, there are two other definite all-Premier League ties with West Brom hosting Norwich and Everton welcoming Fulham to Goodison Park.
Arsenal will be at home to Aston Villa if they can overcome Leeds at the Emirates Stadium on Monday, while Bolton will take on Swansea at the Reebok Stadium if they see off Macclesfield in a replay having drawn 2-2 at Moss Rose on Saturday.
Swindon, who upset the odds to knock out Wigan on Saturday, will face a trip to the east midlands in round four to take on either Nottingham Forest or Leicester.
Crawley will take on Hull after the League Two side knocked Championship club Bristol City out on Saturday.
The ties will be played on January 28, 29 and 30.