Arsenal striker Olivier Giroud has had his claim for wrongful dismissal rejected by the Football Association.
Giroud, 26, was sent off by referee Andre Marriner in the 90th minute of Saturday's 1-0 win at Craven Cottage for his challenge on Stanislav Manolev.
The Gunners decided to appeal the decision, with the forward set to miss the games against Manchester United, Queens Park Rangers and Wigan through suspension.
But Arsene Wenger's side have been unsuccessful with their appeal, meaning he will indeed serve the three-match ban.
An FA statement read: "Following an Independent Regulatory Commission hearing today, Arsenal's Olivier Giroud has had his claim for wrongful dismissal rejected."
Giroud was signed by Arsenal from Montpellier for around £13 million last summer and has scored 11 goals in 33 Premier League appearances during his debut campaign in England.
Wenger must now decide whether to call on Theo Walcott, Lukas Podolski or Gervinho for his team's lone striking role as they look to clinch a top-four finish.