Last year's European champions Chelsea have been drawn against Russian club Rubin Kazan in the quarter-finals of the Europa League.
Chelsea, owned by Russian billionaire Roman Abramovich, will face the side who won back-to-back league titles in 2008 and 2009 but who are struggling in sixth place domestically this season.
Tottenham Hotspur have been paired up with FC Basel. The Swiss side have twice been knocked out of the competition by English clubs in the past decade, with Newcastle dumping them out in 2004 and Middlesbrough beating them in the quarter-finals in 2006.
However, Basel more recently enjoyed success against English opposition, beating Manchester United in last season's Champions League to eliminate them from the competiion.
Turkish club Fenerbahce will face Italian outfit Lazio, while Newcastle United have been spared a third successive trip across Europe after being drawn with Portuguese giants and current Primeira Liga leaders Benfica.