Tony Watt has been ruled out of the second leg of Celtic's Champions League last-16 tie against Juventus in Turin.
The striker bruised his foot in training on Monday and has subsequently not travelled to Italy with the rest of the squad, who are hoping to overturn a 3-0 deficit from the first leg in Glasgow.
The 19-year-old, who scored the ultimately decisive goal in Celtic's memorable 2-1 win over Barcelona in the group stage of this season's competition, joins club captain Scott Brown and full-back Mikael Lustig on the injured list.
Watt came on as a 73rd-minute substitute in the first leg at Parkhead, but could only look on as the Serie A champions put the tie almost beyond reach courtesy of late goals from Claudio Marchisio and Mirko Vucinic to add to Alessandro Matri's early opener.
Despite Celtic's bleak prospects of progressing to the quarter-finals, midfielder Efe Ambrose is not ready to give up on staging a historic comeback at the Juventus Stadium on Wednesday night.
"Everything is possible in football and nobody knows," Ambrose told Celtic's official website. "So let us go there and see what happens as I believe there is still a chance. We played well at Celtic Park but it didn't work in our favour that night. Let´s see what happens in Italy.
"We never give up. That is our major strength. We never throw in the towel and keep fighting to our last breath."