Sir Alex Ferguson is concerned that injury problems will wreck Anderson's career as the hamstrung Brazil midfielder is forced to watch the rest of the season from the sidelines.
Anderson has been blighted by a succession of problems since his £25 million move from FC Porto in 2007 and there are now fears Ferguson will discard the South American as he looks to reinforce his midfield during the summer.
The 24-year-old has been restricted to just 16 appearances this term, and only four since the beginning of November.
Ferguson said: "He hasn't really realised his potential, which is there for all to see.
"He is a fantastic footballer. I just hope he doesn't have the bad luck that Michael Owen has had throughout his career.
"At 24, obviously he's still very young and I'm sure we will get the benefit of that.''
Anderson has won 8 caps for the Brazilian national team.