Wayne Rooney edged one step closer to Sir Bobby Charlton's scoring record by hitting the decisive goal as England won 1-0 in Estonia.
Rooney is now just six shy of becoming England's all-time top scorer thanks to his 74th minute free-kick, which eased England's growing frustration after they had failed to make the most of their opportunities at the A. Le Coq Arena.
Roy Hodgson's team dominated possession, but wasted chances despite playing against 10 men for almost all of the second half following the dismissal of Estonia captain Ragnar Klavan for two yellow cards.
Danny Welbeck and Alex Oxlade-Chamberlain were guilty of missing chances, but the biggest culprit was Rooney, who spurned three good opportunities. England, though, did enough to secure their third straight Euro 2016 qualifying win.
Diego Costa needed his fair share of opportunities to open his goalscoring account for Spain in a 4-0 victory in Luxembourg.
The Brazil-born striker fluffed countless first-half chances to score, with David Silva and Paco Alcacer stepping up to relieve some of the early pressure with a goal apiece.
But Costa registered his first Spain goal in scruffy fashion on 69 minutes, and there was still time for debutant Juan Bernat, a Bayern Munich defender, to score the fourth after coming on as a substitute.
A late exchange of goals saw Russia and Moldova share the points in a 1-1 draw in Moscow.
Fabio Capello's side struggled to break Moldova down for over an hour until Artem Dzjuba was handed the chance to open the scoring from the penalty spot in the 72nd minute.
However, Alexandru Epureanu levelled with a header within two minutes to earn Moldova a share of the spoils.
Sweden picked up the first win of their qualifying campaign, beating Liechtenstein 2-0 in their Group G encounter at the Friends Arena in Solna.
In a quiet first half, Erkan Zengin found the target for Sweden, who were missing leading scorer Zlatan Ibrahimovic due to an Achilles problem.
Jimmy Durmaz doubled their advantage a minute after the break for a Sweden side desperate to register their first win of the campaign after draws against Austria and Russia.
Austria moved clear at the top of the Group G standings as they edged out Montenegro 1-0 at home.
Rubin Okotie's first-half strike was all that separated the teams on the night in Vienna, but it was enough to send Austria two points clear as Russia were held.
While victory by a single goal hardly looked convincing, Austria dominated possession and were worthy winners against a team level on points with them before kick-off.
Milivoje Novakovic's first-half double gave Slovenia a 2-0 win in Lithuania.
The Shimizu S-Pulse striker notched twice in five minutes to decide a match in which his side were deserving winners. The result leaves the two teams level on six points in second place in Group E, three points behind England.
Serhiy Sydorchuk's first-half goal proved enough as Ukraine recorded their second win in four days with a narrow 1-0 victory over Macedonia at Arena Lviv.
Sydorchuk struck just before the break, moments before team-mate Andriy Yarmolenko missed the chance to double their lead as he sent a penalty over the bar.
Mykhaylo Fomenko's Yellow-Blue, who saw off Belarus on Thursday, now have six points from their opening three Group C fixtures.
Captain Marek Hamsik scored two goals as Slovakia registered their second win in four days with a 3-1 victory over Belarus at the Borisov Arena.
Jan Kozak's men claimed a shock 2-1 triumph over Spain on Thursday and maintained their 100 per cent record to stay top Group C, while their opponents remained winless with just one point.
After an uninspiring first half, Hamsik broke the deadlock 20 minutes after the break before Timofey Kalachev struck back for the home side, but Hamsik's second and a late third from Stanislav Sestak sealed the victory.