Young Boys coach Martin Rueda has called on his team to put in a courageous performance against Liverpool at Anfield on Thursday.
The Swiss side are level on six points with the hosts in Group A but their chances of qualifying for the knockout stage will be ended if they lose and Anzhi beat Udinese earlier in the evening.
No Swiss team has won in four visits to Anfield and Liverpool have not lost in eight games against opposition from the country since losing a first meeting against Servette in 1971.
However, back-to-back wins over Udinese - 3-2 victors on Merseyside in early October - has given Rueda confidence they can make amends for their loss to Brendan Rodgers' side in Bern.
``The two games against Udinese have shown us that we can also beat great opponents,'' said Rueda, whose side lost 5-3 to Liverpool in their opening game.
``I expect Liverpool to put out a top team, certainly from the start as they are looking to get into the next stage.
``But it is a game we need something from - there is lots riding on this game.
``We have to be brave and courageous and produce a good performance.
``It is good that Anzhi are playing earlier but it comes down to our performance and we want to get some points.''
England-born defender Scott Sutter, who played youth-team football for Millwall, Aston Villa and Charlton before moving to his father's homeland, is looking forward to sampling the Anfield atmosphere.
``It is special to be playing in England against top teams,'' said the 26-year-old.
``That poses a great test for yourself and gives you a chance to compare yourself with the top stars in the game.''
Veteran defender Mario Raimondi is suspended for the match but goalkeeper and captain Marco Wolfli will feature having played with a thigh injury at the weekend.
Liverpool seemed to have turned a corner in the last couple of weeks and they are unbeaten in seven league matches.
Despite defeat in Moscow a fortnight ago the Reds can also qualify for the knockout stages should Udinese fail to beat Anzhi and the Merseysiders defeat Young Boys.
Boss Brendan Rodgers gets the feeling his side are over their teething troubles in adjusting to a new way of working, although he accepts they are far from the finished article.
``Of course, in that short term you want success and you have to show there is improvement,'' he added.
``I believe we are starting to show improvement and there is a real spirit and unity among us all.
``If we can stay like that and go through the pain together we can get out the other side and restore Liverpool to where it should be.''