Struggling Lille head into their Ligue 1 showdown with Lyon on Sunday with striker Dimitri Payet warning: ``Defeat is forbidden.''
Lille's patchy start to the season took a significant turn for the worse on Wednesday when they were beaten 3-1 in the Champions League by BATE Borisov.
The champions of Belarus had never previously won a group stage match in the competition.
Lille have won just once in Ligue 1 so far this season and last weekend they threw away two points when Troyes snatched a draw with an 88th-minute equaliser.
League leaders Marseille are already nine points ahead with Lyon seven points better off than Rudi Garcia's men.
``Defeat is forbidden,'' Payet said.
``If we manage to start the game well and play like we did in the second period against BATE, then maybe we will have a pleasant surprise.''
Lyon, in contrast, are in buoyant mood after beating Sparta Prague in the Europa League on Thursday, courtesy of second-half goals from Bafetimbi Gomis and Lisandro Lopez.
``I was really impressed by my team,'' said manager Remi Garde.
``I liked the intensity they showed when on the ball and the intelligence of my players.
``We created lots of chances against a team who were not just aggressive but were also well organised in defence.
``We didn't take enough of our chances, and that prevented us from being more relaxed at the end of the game but what I prefer to take away from the game is the control and commitment we showed.''
Lyon will be without defender Mouhamadou Dabo, who suffered a blow to the head last week, and playmaker Yoann Gourcuff.
Lille's Marvin Martin is struggling with an adductor injury suffered against BATE, while Salomon Kalou is suspended.