| Columbus Crew 2010 Picks |
| NAME | POS | COLLEGE/OTHER | RD | PICK (OVR) | HT | WT |
| Dilly Duka | M | | 1 | 1st (8th) | 5-9 |
160 |
| Bright Dike | F | | 1 | 1st (12th) | 6-1 |
223 |
| Kwaku Nyamekye | D | Predator | 4 | 4th (60th) | 6-1 |
200 |
| Othaniel Yanez | M | Condivo | 4 | 4th (61st) | 5-8 |
165 |
| Shaun Francis | D | Lindsey Wilson | 4 | 4th (63rd) | 0-0 |
0 |
H